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KMID : 0881720180330010077
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Journal of Food Hygiene and Safety
2018 Volume.33 No. 1 p.77 ~ p.82
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Protective Effect of Eriobotrya japonica Lindl. on Hepatotoxicity by Carbon Tetrachloride
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Shin Yu-Bin
Ha Bae-Jin
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Abstract
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This study was carried out to investigate the effect of natural Eriobotrya japonica Lindl. vinegar on the liver protective effect of animals exposed to carbon tetrachloride. Eriobotrya japonica Lindl. vinegar (200 mg/kg) was administered at the same time for 28 days, and hepatotoxicity was induced by intraperitoneal injection of carbon tetrachloride on the 29th day. The aspartate aminotransferase and alanine aminotransferase levels were significantly decreased (p < 0.001) and the superoxide dismutase and catalase activities were significantly increased (p < 0.001) in the Eriobotrya japonica Lindl. vinegar group compared to the control group. Histopathological observations showed that the Eriobotrya japonica Lindl. vinegar showed hepatic cell structure similar to normal group, and these results showed that it had an effect of suppressing and protecting the damage of liver cell. Therefore, Eriobotrya japonical Lindl. vinegar is considered to be a healthy functional food of the liver
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KEYWORD
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Aspartate aminotransferase , Alanine aminotransferase , Eriobotrya japonica Lindl. , Hepatotoxicity
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